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Recombinant Human Triple functional domain protein (TRIO), Truncated

ACP21141

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Specifications

Cat.No	ACP21141	Target Name	TRIO
Target Synonyms	ARHGEF23; MEBAS; MRD44; PTPRF-interacting protein; tgat; trio; Trio Rho guanine nucleotide exchange factor; TRIO_HUMAN; Triple functional domain (PTPRF interacting); Triple functional domain protein	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O75962

Background Information

Uniprot Id

O75962
Target Species

Human
Target Name

TRIO
Target Full Name

Triple functional domain protein
Target Function

Guanine nucleotide exchange factor (GEF) for RHOA and RAC1 GTPases. Involved in coordinating actin remodeling, which is necessary for cell migration and growth. Plays a key role in the regulation of neurite outgrowth and lamellipodia formation. In developing hippocampal neurons, limits dendrite formation, without affecting the establishment of axon polarity. Once dendrites are formed, involved in the control of synaptic function by regulating the endocytosis of AMPA-selective glutamate receptors (AMPARs) at CA1 excitatory synapses. May act as a regulator of adipogenesis.
Target Involvement

Mental retardation, autosomal dominant 44 (MRD44)
Target Subcellular Location

Cytoplasm. Cell projection.
Target Protein Families

Protein kinase superfamily, CAMK Ser/Thr protein kinase family
Target Tissue Specificity

Widely expressed, with highest levels in heart, skeletal muscle, and brain.
Target Synonyms

ARHGEF23; MEBAS; MRD44; PTPRF-interacting protein; tgat; trio; Trio Rho guanine nucleotide exchange factor; TRIO_HUMAN; Triple functional domain (PTPRF interacting); Triple functional domain protein

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Recombinant Human Triple functional domain protein (TRIO), Truncated

Specifications

Immunogen Information

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