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| Cat.No | ACP21158 | Target Name | NPM3 |
|---|---|---|---|
| Target Synonyms | 3; Nucleoplasmin 3; Nucleoplasmin-3; PORMIN; RGD1565542; TMEM123, member 3; nucleophosmin/nucleoplasmin, NPM 3; NPM3; NPM3_HUMAN; Nub1; nucleophosmin/nucleoplasmin family | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-178 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O75607 |
|---|
Uniprot Id
O75607
Target Species
Human
Target Name
NPM3
Target Full Name
Nucleoplasmin-3
Target Function
Plays a role in the regulation of diverse cellular processes such as ribosome biogenesis, chromatin remodeling or protein chaperoning. Modulates the histone chaperone function and the RNA-binding activity of nucleolar phosphoprotein B23/NPM. Efficiently mediates chromatin remodeling when included in a pentamer containing NPM3 and NPM.
Target Subcellular Location
Nucleus. Nucleus, nucleolus.
Target Protein Families
Nucleoplasmin family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
NPM 3; NPM3; NPM3_HUMAN; Nub1; nucleophosmin/nucleoplasmin family, member 3; nucleophosmin/nucleoplasmin, 3; Nucleoplasmin 3; Nucleoplasmin-3; PORMIN; RGD1565542; TMEM123
Target Background
The protein encoded by this gene is related to the nuclear chaperone phosphoproteins, nucleoplasmin and nucleophosmin. This protein is strongly expressed in diverse cell types where it localizes primarily to the nucleus. Based on its similarity to nucleoplasmin and nucleophosmin, this protein likely functions as a molecular chaperone in the cell nucleus.
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