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| Cat.No | ACP21334 | Target Name | TDRD6 |
|---|---|---|---|
| Target Synonyms | TDRD6; Tudor domain-containing protein 6; Antigen NY-CO-45; Cancer/testis antigen 41.2; CT41.2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O60522 |
|---|
Uniprot Id
O60522
Target Species
Human
Target Name
TDRD6
Target Full Name
Tudor domain-containing protein 6
Target Function
Tudor domain-containing protein involved in germ cell development, more specifically the formation of chromatoid body (during spermiogenesis), Balbiani body (during oogenesis), germ plasm (upon fertilization), and for proper miRNA expression and spliceosome maturation. Essential for RNA-dependent helicase UPF1 localization to chromatoid body, for UPF1-UPF2 and UPF1-DDX4 interactions which are required for mRNA degradation, using the extended 3' UTR-triggered nonsense-mediated mRNA decay (NMD) pathway. Involved in spliceosome maturation and mRNA splicing in prophase I spermatocytes through interaction with arginine N-methyltransferase PRMT5 and symmetrically arginine dimethylated SNRPB (small nuclear ribonucleoprotein-associated protein)
Target Subcellular Location
Cytoplasm.
Target Synonyms
TDRD6; Tudor domain-containing protein 6; Antigen NY-CO-45; Cancer/testis antigen 41.2; CT41.2
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