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| Cat.No | ACP21459 | Target Name | PFDN6 |
|---|---|---|---|
| Target Synonyms | H2 KE2; H2KE2; HKE2; HLA class II region expressed gene KE2; KE 2; KE2; KE2 protein; KE2, homolog of; PFD6_HUMAN; Pfdn6; Prefoldin subunit 6; Protein Ke2, mouse | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-129 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O15212 |
|---|
Uniprot Id
O15212
Target Species
Human
Target Name
PFDN6
Target Full Name
Prefoldin subunit 6
Target Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Target Protein Families
Prefoldin subunit beta family
Target Synonyms
H2 KE2; H2KE2; HKE2; HLA class II region expressed gene KE2; KE 2; KE2; KE2 protein; KE2, mouse, homolog of; PFD6_HUMAN; Pfdn6; Prefoldin subunit 6; Protein Ke2
Target Background
PFDN6 is a subunit of the heteromeric prefoldin complex that chaperones nascent actin (see MIM 102560) and alpha- and beta-tubulin (see MIM 602529 and MIM 191130, respectively) chains pending their transfer to the cytosolic chaperonin containing TCP1 (MIM 186980) (CCT) complex (Hansen et al., 1999 [PubMed 10209023]).
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