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Recombinant Human Complexin-1 (CPLX1)

ACP21556

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Specifications

Cat.No	ACP21556	Target Name	CPLX1
Target Synonyms	921-S; complexin 1; Complexin I; Complexin-1; CPLX1; CPLX1_HUMAN; CPX I; CPX-I; CPX1; Synaphin 2; Synaphin-2	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-134
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O14810

Background Information

Uniprot Id

O14810
Target Species

Human
Target Name

CPLX1
Target Full Name

Complexin-1
Target Function

Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior.
Target Subcellular Location

Cytoplasm, cytosol. Perikaryon. Cell junction, synapse, presynapse.
Target Protein Families

Complexin/synaphin family
Target Tissue Specificity

Nervous system. In hippocampus and cerebellum, expressed mainly by inhibitory neurons. Overexpressed in substantia nigra from patients with Parkinson disease.
Target Synonyms

921-S; complexin 1; Complexin I; Complexin-1; CPLX1; CPLX1_HUMAN; CPX I; CPX-I; CPX1; Synaphin 2; Synaphin-2

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Recombinant Human Complexin-1 (CPLX1)

Specifications

Immunogen Information

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