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Recombinant Human Growth/differentiation factor 8 (MSTN)

ACP21641

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Specifications

Cat.No	ACP21641	Target Name	MSTN
Target Synonyms	Cmpt; GDF-8; GDF8_HUMAN; Growth/differentiation factor 8; MSLHP; MSTN; MSTN myostatin; Myostatin; Myostatin Propeptide	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	267-375
Protein Length	Full Length of Mature Protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O14793

Background Information

Uniprot Id

O14793
Target Species

Human
Target Name

MSTN
Target Full Name

Growth/differentiation factor 8
Target Function

Acts specifically as a negative regulator of skeletal muscle growth.
Target Involvement

Muscle hypertrophy (MSLHP)
Target Subcellular Location

Secreted.
Target Protein Families

TGF-beta family
Target Research Area

Signal Transduction
Target Synonyms

Cmpt; GDF-8; GDF8_HUMAN; Growth/differentiation factor 8; MSLHP; MSTN; MSTN myostatin; Myostatin; Myostatin Propeptide
Target Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals.

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Recombinant Human Growth/differentiation factor 8 (MSTN)

Specifications

Immunogen Information

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