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Recombinant Human Protein Wnt-9a (WNT9A)

ACP21724

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP21724 Target NameWNT9A
Target Synonymsmember 14; Wnt 14; Wnt 9a; WNT14; WNT9A; WNT9A_HUMAN, member 9A; wingless-type MMTV integration site family, MGC138165; MGC141991; Protein Wnt-14; Protein Wnt-9a; RP23-378H5.1; Wingless related MMTV integration site 9A; Wingless type MMTV integration site 9A; Wingless type MMTV integration site familyFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range30-365
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO14904
Background Information
  • Uniprot Id

    O14904

  • Target Species

    Human

  • Target Name

    WNT9A

  • Target Full Name

    Protein Wnt-9a

  • Target Function

    Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal timing of IHH expression during embryonic bone development, normal chondrocyte maturation and for normal bone mineralization during embryonic bone development. Plays a redundant role in maintaining joint integrity.

  • Target Subcellular Location

    Secreted, extracellular space, extracellular matrix. Secreted.

  • Target Protein Families

    Wnt family

  • Target Synonyms

    MGC138165; MGC141991; Protein Wnt-14; Protein Wnt-9a; RP23-378H5.1; Wingless related MMTV integration site 9A; Wingless type MMTV integration site 9A; Wingless type MMTV integration site family, member 9A; wingless-type MMTV integration site family, member 14; Wnt 14; Wnt 9a; WNT14; WNT9A; WNT9A_HUMAN

  • Target Background

    The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is expressed in gastric cancer cell lines. The protein encoded by this gene shows 75% amino acid identity to chicken Wnt14, which has been shown to play a central role in initiating synovial joint formation in the chick limb. This gene is clustered with another family member, WNT3A, in the chromosome 1q42 region.

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