Recombinant Human Interferon-related developmental regulator 1 (IFRD1)

Uniprot Id

O00458

Target Species

Human

Target Name

IFRD1

Target Full Name

Interferon-related developmental regulator 1

Target Function

Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal.

Target Protein Families

IFRD family

Target Tissue Specificity

Expressed in a variety of tissues.

Target Synonyms

12 O tetradecanoylphorbol 13 acetate induced sequence 7; IFRD1; IFRD1_HUMAN; interferon related developmental regulator 1; Interferon-related developmental regulator 1; Nerve growth factor inducible protein PC4 ; Nerve growth factor-inducible protein PC4; PC4; Pheochromocytoma cell 4; TIS7; TPA induced sequence 7

Target Background

This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants.