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| Cat.No | ACP22693 | Target Name | MAZ |
|---|---|---|---|
| Target Synonyms | 87 kilodaltons; ZNF801 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-477 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P56270 |
|---|
Uniprot Id
P56270
Target Species
Human
Target Name
MAZ
Target Full Name
Myc-associated zinc finger protein
Target Function
Transcriptional regulator, potentially with dual roles in transcription initiation and termination.; Binds DNA and functions as a transcriptional activator. Binds to two G/A-rich sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.; Binds DNA and functions as a transcriptional activator. Inhibits MAZ isoform 1-mediated transcription.; Binds DNA and functions as a transcriptional activator.
Target Subcellular Location
Nucleus. Note=In brains of Alzheimer disease patients, present in a plaque-like structures.
Target Tissue Specificity
Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).; [Isoform 1]: Expressed in the heart, brain, placenta, lung, liver, skeletal muscle and weakly expressed in the kidney. Ex
Target Synonyms
MAZ; MAZ_HUMAN; MAZI; MYC associated zinc finger protein ; Myc-associated zinc finger protein; Pur-1; Pur1; Purine binding transcription factor ; Purine-binding transcription factor; SAF 1; SAF 2; SAF-1; SAF-2; SAF-3; Serum amyloid A activating factor 1; Serum amyloid A activating factor 2; Transcription factor Zif87; ZF87; Zif87; Zinc finger protein 801; Zinc finger protein, 87 kilodaltons; ZNF801
Target Background
Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including regulation of gene expression; regulation of signal transduction; and transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus.
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