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| Cat.No | ACP22840 | Target Name | CHN2 |
|---|---|---|---|
| Target Synonyms | CHN2; ARHGAP3; BCH; Beta-chimaerin; Beta-chimerin; Rho GTPase-activating protein 3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-468 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P52757 |
|---|
Uniprot Id
P52757
Target Species
Human
Target Name
CHN2
Target Full Name
Beta-chimaerin
Target Function
GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and could therefore play a role in the progression from low-grade to high-grade tumors.
Target Subcellular Location
Membrane; Peripheral membrane protein.
Target Tissue Specificity
Highest levels in the brain and pancreas. Also expressed in the heart, placenta, and weakly in the kidney and liver. Expression is much reduced in the malignant gliomas, compared to normal brain or low-grade astrocytomas.
Target Synonyms
CHN2; ARHGAP3; BCH; Beta-chimaerin; Beta-chimerin; Rho GTPase-activating protein 3
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