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| Cat.No | ACP22997 | Target Name | CCNG1 |
|---|---|---|---|
| Target Synonyms | CCNG 1; CCNG; CCNG1; CCNG1_HUMAN; CYCG1; Cyclin G; Cyclin G1; Cyclin-G; Cyclin-G1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-295 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P51959 |
|---|
Uniprot Id
P51959
Target Species
Human
Target Name
CCNG1
Target Full Name
Cyclin-G1
Target Function
May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
Target Subcellular Location
Nucleus. Note=DNA replication foci after DNA damage.
Target Protein Families
Cyclin family, Cyclin G subfamily
Target Tissue Specificity
High levels in skeletal muscle, ovary, kidney and colon.
Target Synonyms
CCNG 1; CCNG; CCNG1; CCNG1_HUMAN; CYCG1; Cyclin G; Cyclin G1; Cyclin-G; Cyclin-G1
Target Background
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene.
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