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| Cat.No | ACP23001 | Target Name | GZMM |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 26-257 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P51124 |
|---|
Uniprot Id
P51124
Target Species
Human
Target Name
GZMM
Target Full Name
Granzyme M
Target Function
Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.
Target Subcellular Location
Secreted. Cytoplasmic granule. Note=Granules of large granular lymphocytes.
Target Protein Families
Peptidase S1 family, Granzyme subfamily
Target Tissue Specificity
Highly and constitutively expressed in activated natural killer (NK) cells.
Target Synonyms
GRAM_HUMAN; Granzyme M (lymphocyte met ase 1); Granzyme M; GranzymeM; GZM M; Gzmm; HU Met 1; HU-Met-1; LMET 1; LMET1; Lymphocyte met ase 1; MET 1; Met 1 serine protease; Met ase; Met-1 serine protease; Met-ase; MET1; Met1 serine protease; Natural killer cell granular protease
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