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Recombinant Human Tissue factor pathway inhibitor 2 (TFPI2)

ACP23085

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP23085 Target NameTFPI2
Target SynonymsPlacental protein 5; PP5; REF1; Retinal pigment epithelium cell factor 1; TFPI 2; TFPI-2; TFPI2; TFPI2 PEN; TFPI2_HUMAN; Tissue factor pathway inhibitor 2FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range23-235
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP48307
Background Information
  • Uniprot Id

    P48307

  • Target Species

    Human

  • Target Name

    TFPI2

  • Target Full Name

    Tissue factor pathway inhibitor 2

  • Target Function

    May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin.

  • Target Subcellular Location

    Secreted.

  • Target Tissue Specificity

    Umbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy.

  • Target Synonyms

    Placental protein 5; PP5; REF1; Retinal pigment epithelium cell factor 1; TFPI 2; TFPI-2; TFPI2; TFPI2 PEN; TFPI2_HUMAN; Tissue factor pathway inhibitor 2

  • Target Background

    This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants.

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