Recombinant Human Heat shock 70 kDa protein 1-like (HSPA1L)

Cat.No	ACP23253	Target Name	HSPA1L
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-641	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP23253

Target Name

HSPA1L

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

1-641

Protein Length

Full length protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	P34931

Background Information

Uniprot Id

P34931
Target Species

Human
Target Name

HSPA1L
Target Full Name

Heat shock 70 kDa protein 1-like
Target Function

Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release. Positive regulator of PRKN translocation to damaged mitochondria.
Target Protein Families

Heat shock protein 70 family
Target Tissue Specificity

Expressed in spermatids.
Target Synonyms

Heat shock 70 kDa protein 1 Hom ; Heat shock 70 kDa protein 1 like ; Heat shock 70 kDa protein 1-Hom; Heat shock 70 kDa protein 1-like; Heat shock 70 kDa protein 1L; Heat shock 70kD protein like 1; HS71L_HUMAN; HSP70 1L; HSP70 HOM ; HSP70-Hom; HSPA1L; hum70t; Spermatid specific heat shock protein 70
Target Background

This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein.

Recombinant Human Heat shock 70 kDa protein 1-like (HSPA1L)

Specifications

Immunogen Information

Inquire Recombinant Human Heat shock 70 kDa protein 1-like (HSPA1L) Now

Related Products