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Recombinant Human Protein S100-A7 (S100A7)

ACP23547

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP23547 Target NameS100A7
Target SynonymsHID 5; Protein S100 A7; Protein S100-A7; PSOR 1; PSOR1; Psoriasin 1; Psoriasin; Psoriasin1; S100 Calcium binding protein A7; S100 calcium-binding protein A7; S100A7; S100A7c; S10A7_HUMANFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range2-101
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP31151
Background Information
  • Uniprot Id

    P31151

  • Target Species

    Human

  • Target Name

    S100A7

  • Target Full Name

    Protein S100-A7

  • Target Subcellular Location

    Cytoplasm. Secreted. Note=Secreted by a non-classical secretory pathway.

  • Target Protein Families

    S-100 family

  • Target Tissue Specificity

    Fetal ear, skin, and tongue and human cell lines. Highly up-regulated in psoriatic epidermis. Also highly expressed in the urine of bladder squamous cell carcinoma (SCC) bearing patients.

  • Target Synonyms

    HID 5; Protein S100 A7; Protein S100-A7; PSOR 1; PSOR1; Psoriasin 1; Psoriasin; Psoriasin1; S100 Calcium binding protein A7; S100 calcium-binding protein A7; S100A7; S100A7c; S10A7_HUMAN

  • Target Background

    The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.

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