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Recombinant Human Myeloid cell nuclear differentiation antigen (MNDA)

ACP23779

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP23779 Target NameMNDA
Target SynonymsMNDA; MNDA_HUMAN; Myeloid cell nuclear differentiation antigen; OTTHUMP00000024384; PYHIN3FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-407
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP41218
Background Information
  • Uniprot Id

    P41218

  • Target Species

    Human

  • Target Name

    MNDA

  • Target Full Name

    Myeloid cell nuclear differentiation antigen

  • Target Function

    May act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell-specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1.

  • Target Subcellular Location

    Nucleus. Cytoplasm. Note=Uniformly distributed throughout the interphase cell nucleus. Associates with chromatin.

  • Target Tissue Specificity

    Expressed constitutively in cells of the myeloid lineage. Found in promyelocyte stage cells as well as in all other stage cells including peripheral blood monocytes and granulocytes. Also appears in myeloblast cells in some cases of acute myeloid Leukemia

  • Target Synonyms

    MNDA; MNDA_HUMAN; Myeloid cell nuclear differentiation antigen; OTTHUMP00000024384; PYHIN3

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