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Recombinant Human Folate receptor beta (FOLR2)

ACP24237

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP24237 Target NameFOLR2
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range17-230Protein LengthFull Length of Mature Protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP14207
Background Information
  • Uniprot Id

    P14207

  • Target Species

    Human

  • Target Name

    FOLR2

  • Target Full Name

    Folate receptor beta

  • Target Function

    Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.

  • Target Subcellular Location

    Cell membrane; Lipid-anchor, GPI-anchor. Secreted.

  • Target Protein Families

    Folate receptor family

  • Target Tissue Specificity

    Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues.

  • Target Research Area

    Metabolism

  • Target Synonyms

    beta hFR; FBP; FBP/PL 1; FBP2; fetal/placental; folate receptor 2 (fetal); Folate receptor 2; Folate receptor; Folate receptor beta; Folate receptor; fetal/placental; Folbp 2; Folbp2; Folr2; FOLR2_HUMAN; FR beta; FR P3; FR-beta; Placental folate binding protein; Placental folate-binding protein

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