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Recombinant Human Lysosomal protective protein (CTSA)

ACP24386

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP24386 Target NameCTSA
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range29-480Protein LengthFull Length of Mature Protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP10619
Background Information
  • Uniprot Id

    P10619

  • Target Species

    Human

  • Target Name

    CTSA

  • Target Full Name

    Lysosomal protective protein

  • Target Function

    Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.

  • Target Involvement

    Galactosialidosis (GSL)

  • Target Subcellular Location

    Lysosome.

  • Target Protein Families

    Peptidase S10 family

  • Target Synonyms

    beta galactosidase 2; BETA GALACTOSIDASE PROTECTIVE PROTEIN; beta-galactosidase 2; beta-galactosidase protective protein; betagalactosidase 2; Carboxypeptidase C; Carboxypeptidase L; carboxypeptidase Y-like kininase; Cathepsin A; Ctsa; deamidase; EC 3.4.16.5; Glactosialidosis; GLB2; Goldberg Syndrome; GSL; lysosomal carboxypeptidase A; Lysosomal protective protein 20 kDa chain; Lysosomal protective protein; Lysosomal protective protein deficiency; NEURAMINIDASE BETA GALACTOSIDASE EXPRESSION; NGBE; Neuraminidase deficiency with beta-galactosidase deficiency; NGBE; OTTHUMP00000031778; OTTHUMP00000031781 ; PPCA; PPCA deficiency; PPGB; PPGB_HUMAN; Protective protein cathepsin A; Protective protein for beta galactosidase ; Protective protein for beta-galactosidase; Protective protein/cathepsin A deficiency; urinary kininase

  • Target Background

    This gene encodes a member of the peptidase S10 family of serine carboxypeptidases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate two chains that comprise the heterodimeric active enzyme. This enzyme possesses deamidase, esterase and carboxypeptidase activities and acts as a scaffold in the lysosomal multienzyme complex. Mutations in this gene are associated with galactosialidosis.

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