Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP1B (FKBP1B)

Cat.No	ACP24648	Target Name	FKBP1B
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	2-108	Protein Length	Full Length of Mature Protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP24648

Target Name

FKBP1B

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

2-108

Protein Length

Full Length of Mature Protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	P68106

Background Information

Uniprot Id

P68106
Target Species

Human
Target Name

FKBP1B
Target Full Name

Peptidyl-prolyl cis-trans isomerase FKBP1B
Target Function

Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Target Subcellular Location

Cytoplasm. Sarcoplasmic reticulum.
Target Protein Families

FKBP-type PPIase family, FKBP1 subfamily
Target Tissue Specificity

Detected in heart muscle (at protein level). Isoform 1 and isoform 2 are ubiquitous with highest levels in brain and thymus.
Target Synonyms

12.6 kDa FK506-binding protein; 12.6 kDa FKBP; Calstabin 2; FK506 binding protein 1 like; FK506 binding protein 12.6; FK506 binding protein 1B 12.6 kDa; FK506 binding protein 1B; FK506-binding protein 1B; FKB1B_HUMAN; FKBP 12.6; FKBP 1B; FKBP 1L; FKBP 9; FKBP-12.6; FKBP-1B; FKBP12.6; Fkbp1b; FKBP1L; FKBP9; h FKBP 12; h-FKBP-12; Immunophilin FKBP12.6; OTK 4; OTK4; Peptidyl prolyl cis trans isomerase 1B; Peptidyl prolyl cis trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP1B; PKBP 1L; PKBP1L; PPIase 1B; PPIase; PPIase FKBP1B; Rotamase 1B; Rotamase
Target Background

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.

Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP1B (FKBP1B)

Specifications

Immunogen Information

Inquire Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP1B (FKBP1B) Now

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