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The antibody against OLFML3 was raised in rabbit using the Recombinant Human Olfactomedin-like protein 3 protein (201-406AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against OLFML3 was raised in rabbit using the Recombinant Human Olfactomedin-like protein 3 protein (201-406AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human placenta tissue using OLFML3 Antibody at dilution of 1:1002
| Cat.No | ADC-10045A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | OLFML3 |
| Target Synonyms | HNOEL-iso antibody; hOLF44 antibody; OLF44 antibody; Olfactomedin like 3 antibody; Olfactomedin-like protein 3 antibody; OLFL3_HUMAN antibody; OLFML3 antibody | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Olfactomedin-like protein 3 protein (201-406AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NRN5 |
Uniprot Id
Q9NRN5
Target Species
Human
Target Name
OLFML3
Target Full Name
Olfactomedin-like protein 3
Target Function
Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation. May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes.
Target Subcellular Location
Secreted.
Target Protein Families
OLFML3 family
Target Tissue Specificity
Abundant in placenta, moderate in liver and heart, whereas fairly weak in other tissues examined. On term placenta, mainly localized extracellularly surrounding the syncytiotrophoblastic cells and very rarely expressed in the maternal decidua layer.
Target Synonyms
HNOEL-iso; hOLF44; OLF44; Olfactomedin like 3; Olfactomedin-like protein 3; OLFL3_HUMAN; OLFML3
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