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The antibody against pfo was raised in rabbit using the Recombinant Clostridium perfringens Perfringolysin O protein (29-500AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against pfo was raised in rabbit using the Recombinant Clostridium perfringens Perfringolysin O protein (29-500AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-12209A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | pfo |
| Target Synonyms | pfo antibody; pfoA antibody; pfoR antibody; CPE0163 antibody; Perfringolysin O antibody; Theta-toxin antibody; Thiol-activated cytolysin antibody | Form | Liquid |
| Species Reactivity | Clostridium perfringens | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Clostridium perfringens Perfringolysin O protein (29-500AA) | Target Species | Clostridium perfringens |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P0C2E9 |
Uniprot Id
P0C2E9
Target Species
Clostridium perfringens
Target Name
PFO
Target Function
A cholesterol-dependent toxin that causes cytolysis by forming pores in cholesterol-containing host membranes. After binding to target membranes, the protein assembles into a pre-pore complex. A major conformational change leads to insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol is required for binding to host cell membranes, membrane insertion and pore formation; cholesterol binding is mediated by a Thr-Leu pair in the C-terminus. Can be reversibly inactivated by oxidation.
Target Subcellular Location
Secreted. Host cell membrane; Multi-pass membrane protein.
Target Protein Families
Thiol-activated cytolysin family
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