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The antibody against MBL2 was raised in rabbit using the Synthetic peptide from Human protein at AA range: 21-70 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against MBL2 was raised in rabbit using the Synthetic peptide from Human protein at AA range: 21-70 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
Western Blot analysis of mouse-kidney cells using Antibody diluted at 500. Secondary antibody was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:2002
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:2003
| Cat.No | ADC-13078A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MBL2 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Storage Buffer | PH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBS | Purification Method | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide from Human protein at AA range: 21-70 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P11226 |
Uniprot Id
P11226
Target Species
Human
Target Name
MBL2
Target Full Name
Mannose-binding protein C
Target Function
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
Target Subcellular Location
Secreted.
Target Tissue Specificity
Plasma protein produced mainly in the liver.
Target Research Area
Immunology
Target Synonyms
COLEC 1; COLEC1; Collectin-1; HSMBPC; Lectin; mannose-binding; soluble; 2; Mannan binding lectin; Mannan binding protein; Mannan-binding protein; Mannose binding lectin (protein C) 2 soluble; Mannose binding lectin (protein C) 2; soluble (opsonic defect); Mannose binding lectin (protein C) 2; soluble; Mannose binding lectin 2 soluble; Mannose binding lectin 2; soluble (opsonic defect); Mannose binding lectin; Mannose binding lectin protein C2 soluble opsonic defect; Mannose binding protein; Mannose binding protein C; Mannose binding protein C precursor ; Mannose binding protein; serum; Mannose-binding lectin; Mannose-binding protein C; MBL 2; MBL; MBL2; MBL2_HUMAN; MBL2D; MBP 1; MBP; MBP C; MBP-C; MBP1; MBPB; MBPC; MBPD; MGC116832; MGC116833; Opsonic defect; protein C; Soluble mannose binding lectin
Target Background
This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes and binds to mannose and N-acetylglucosamine on many microorganisms, including bacteria, yeast, and viruses including influenza virus, HIV and SARS-CoV. This binding activates the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.
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