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The antibody against NOP56 was raised in rabbit using the Synthesized peptide derived from NOP56 at AA range: 191-240 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against NOP56 was raised in rabbit using the Synthesized peptide derived from NOP56 at AA range: 191-240 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
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Western Blot analysis of HEPG2 Hela cells using NOP56 Polyclonal Antibody diluted at 1:1000. Secondary antibody was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-placenta, antibody was diluted at 1:2002
Immunohistochemical analysis of paraffin-embedded human-placenta, antibody was diluted at 1:2003
| Cat.No | ADC-13092A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NOP56 |
| Target Synonyms | NOP56 antibody; NOL5ANucleolar protein 56 antibody; Nucleolar protein 5A antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from NOP56 at AA range: 191-240 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O00567 |
Uniprot Id
O00567
Target Species
Human
Target Name
NOP56
Target Full Name
Nucleolar protein 56
Target Function
Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs.
Target Involvement
Spinocerebellar ataxia 36 (SCA36)
Target Subcellular Location
Nucleus, nucleolus. Cytoplasm. Nucleus, nucleoplasm.
Target Protein Families
NOP5/NOP56 family
Target Synonyms
NOP56; NOL5ANucleolar protein 56; Nucleolar protein 5A
Target Background
Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined.
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