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The antibody against RETREG1 was raised in rabbit using the Recombinant Human Reticulophagy receptor FAM134B protein (1-131AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against RETREG1 was raised in rabbit using the Recombinant Human Reticulophagy receptor FAM134B protein (1-131AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human pancreatic tissue using FAM134B Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skin tissue using FAM134B Antibody at dilution of 1:1002
| Cat.No | ADC-13238A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RETREG1 |
| Target Synonyms | RETREG1; FAM134B; JK1; Reticulophagy regulator 1; Reticulophagy receptor 1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Reticulophagy receptor FAM134B protein (1-131AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H6L5 |
Uniprot Id
Q9H6L5
Target Species
Human
Target Name
RETREG1
Target Full Name
Reticulophagy regulator 1
Target Function
Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes. Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins. Required for long-term survival of nociceptive and autonomic ganglion neurons.
Target Involvement
Neuropathy, hereditary sensory and autonomic, 2B (HSAN2B)
Target Subcellular Location
Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
RETREG family
Target Tissue Specificity
Overexpressed in esophageal squamous cell carcinoma.
Target Synonyms
RETREG1; FAM134B; JK1; Reticulophagy regulator 1; Reticulophagy receptor 1
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