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The antibody against C2CD3 was raised in rabbit using the Recombinant Human C2 domain-containing protein 3 protein (2079-2265AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against C2CD3 was raised in rabbit using the Recombinant Human C2 domain-containing protein 3 protein (2079-2265AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human testis tissue using C2CD3 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human thyroid tissue using C2CD3 Antibody at dilution of 1:1002
Immunofluorescent analysis of Hela cells using C2CD3 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-14334A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | C2CD3 |
| Target Synonyms | C2CD3 antibody; C2 domain-containing protein 3 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human C2 domain-containing protein 3 protein (2079-2265AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q4AC94 |
Uniprot Id
Q4AC94
Target Species
Human
Target Name
C2CD3
Target Full Name
C2 domain-containing protein 3
Target Function
Component of the centrioles that acts as a positive regulator of centriole elongation. Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation. Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3.
Target Involvement
Orofaciodigital syndrome 14 (OFD14)
Target Subcellular Location
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to centrioles and procentrioles both in interphase and mitosis. Localizes to centriolar satellites, localization is dependent on PCM1 and dynein-mediated retrograde transport. Also localizes to the distal ends of the mother and daughter centrioles.
Target Synonyms
C2CD3; C2 domain-containing protein 3
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