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Rabbit anti-Human RND3 Polyclonal Antibody

The antibody against RND3 was raised in rabbit using the Recombinant Human Rho-related GTP-binding protein RhoE protein (152-239AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

ADC-14593A

The antibody against RND3 was raised in rabbit using the Recombinant Human Rho-related GTP-binding protein RhoE protein (152-239AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-14593A ClonalityPolyclonal
Host SpeciesRabbitTarget NameRND3
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Rho-related GTP-binding protein RhoE protein (152-239AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP61587
Background Information
  • Uniprot Id

    P61587

  • Target Species

    Human

  • Target Name

    RND3

  • Target Full Name

    Rho-related GTP-binding protein RhoE

  • Target Function

    Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

  • Target Subcellular Location

    Golgi apparatus membrane; Peripheral membrane protein.

  • Target Protein Families

    Small GTPase superfamily, Rho family

  • Target Tissue Specificity

    Ubiquitous.

  • Target Synonyms

    ARHE; memB; Protein MemB; Ras homolog gene family member E; Rho family GTPase 3; Rho-related GTP-binding protein Rho8; Rho-related GTP-binding protein RhoE; Rho8; RhoE; Rnd3; RND3_HUMAN; Small GTP binding protein Rho8

  • Target Background

    This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified.

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