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The antibody against KANSL1 was raised in rabbit using the Recombinant Human KAT8 regulatory NSL complex subunit 1 protein (815-1086AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against KANSL1 was raised in rabbit using the Recombinant Human KAT8 regulatory NSL complex subunit 1 protein (815-1086AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
$299.00
| Cat.No | ADC-15285A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KANSL1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | FITC conjugated |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human KAT8 regulatory NSL complex subunit 1 protein (815-1086AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q7Z3B3 |
Uniprot Id
Q7Z3B3
Target Species
Human
Target Name
KANSL1
Target Full Name
KAT8 regulatory NSL complex subunit 1
Target Function
As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
Target Subcellular Location
Nucleus. Nucleus. Chromosome, centromere, kinetochore.
Target Tissue Specificity
Expressed in the brain.
Target Synonyms
CENP-36; centromere protein 36; DKFZp686P06109; DKFZp727C091; hMSL1v1; hypothetical protein LOC284058; K1267_HUMAN; KANSL1; KAT8 regulatory NSL complex subunit 1; KDVS; KIAA1267; male-specific lethal 1 homolog; MGC102843; MLL1/MLL complex subunit KIAA1267; MSL1 homolog 1; MSL1v1; Non specific lethal 1 homolog; NSL complex protein NSL1; NSL1
Target Background
This gene encodes a nuclear protein that is a subunit of two protein complexes involved with histone acetylation, the MLL1 complex and the NSL1 complex. The encoded protein has been implicated in a variety of cellular processes including enhancer regulation, cell proliferation, and mitosis. Mutations in this gene are associated with Koolen-de Vries Syndrome.
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