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The antibody against DARS2 was raised in rabbit using the Recombinant Human Aspartate--tRNA ligase, mitochondrial protein (489-628AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against DARS2 was raised in rabbit using the Recombinant Human Aspartate–tRNA ligase, mitochondrial protein (489-628AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-15330A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DARS2 |
| Target Synonyms | DARS2 antibody; Aspartate--tRNA ligase antibody; mitochondrial antibody; EC 6.1.1.12 antibody; Aspartyl-tRNA synthetase antibody; AspRS antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Aspartate--tRNA ligase, mitochondrial protein (489-628AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6PI48 |
Uniprot Id
Q6PI48
Target Species
Human
Target Name
DARS2
Target Full Name
Aspartate--tRNA ligase, mitochondrial
Target Involvement
Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Class-II aminoacyl-tRNA synthetase family, Type 1 subfamily
Target Synonyms
DARS2; Aspartate--tRNA ligase; mitochondrial; EC 6.1.1.12; Aspartyl-tRNA synthetase; AspRS
Target Background
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).
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