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The antibody against HS6ST1 was raised in rabbit using the Recombinant Human Heparan-sulfate 6-O-sulfotransferase 1 protein (3-133AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against HS6ST1 was raised in rabbit using the Recombinant Human Heparan-sulfate 6-O-sulfotransferase 1 protein (3-133AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-15971A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HS6ST1 |
| Target Synonyms | HS6ST1; HS6ST; Heparan-sulfate 6-O-sulfotransferase 1; HS6ST-1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | HRP conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Heparan-sulfate 6-O-sulfotransferase 1 protein (3-133AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O60243 |
Uniprot Id
O60243
Target Species
Human
Target Name
HS6ST1
Target Full Name
Heparan-sulfate 6-O-sulfotransferase 1
Target Function
6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid.
Target Involvement
Hypogonadotropic hypogonadism 15 with or without anosmia (HH15)
Target Subcellular Location
Membrane; Single-pass type II membrane protein.
Target Protein Families
Sulfotransferase 6 family
Target Tissue Specificity
Expressed in fetal brain.
Target Research Area
Neuroscience
Target Synonyms
HS6ST1; HS6ST; Heparan-sulfate 6-O-sulfotransferase 1; HS6ST-1
Target Background
The protein encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biological activities. This enzyme is a type II integral membrane protein and is responsible for 6-O-sulfation of heparan sulfate. This enzyme does not share significant sequence similarity with other known sulfotransferases. A pseudogene located on chromosome 1 has been found for this gene.
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