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The antibody against MEMO1 was raised in rabbit using the Recombinant Human Protein MEMO1 protein (1-297AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against MEMO1 was raised in rabbit using the Recombinant Human Protein MEMO1 protein (1-297AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human thyroid tissue using MEMO1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using MEMO1 Antibody at dilution of 1:1002
| Cat.No | ADC-16547A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MEMO1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein MEMO1 protein (1-297AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y316 |
Uniprot Id
Q9Y316
Target Species
Human
Target Name
MEMO1
Target Full Name
Protein MEMO1
Target Function
May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.
Target Protein Families
MEMO1 family
Target Research Area
Signal Transduction
Target Synonyms
C21orf19-like protein; C2orf4; CGI 27; DKFZp434I0135; FLJ25031; HCV NS5A-transactivated protein 7; Hepatitis C virus NS5A-transactivated protein 7; Mediator of cell motility 1; Mediator of ErbB2-driven cell motility 1; MEMO; Memo-1; memo1; MEMO1_HUMAN; NS5ATP7; Protein MEMO1
Target Background
Involved in regulation of microtubule-based process. Located in cytosol and nucleus.
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