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The antibody against TRIM10 was raised in rabbit using the Recombinant Human Tripartite motif-containing protein 10 protein (222-481AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against TRIM10 was raised in rabbit using the Recombinant Human Tripartite motif-containing protein 10 protein (222-481AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human breast cancer using TRIM10 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human small intestine tissue using TRIM10 Antibody at dilution of 1:1002
| Cat.No | ADC-16588A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TRIM10 |
| Target Synonyms | TRIM10 antibody; RFB30 antibody; RNF9 antibody; Tripartite motif-containing protein 10 antibody; B30-RING finger protein antibody; RING finger protein 9 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Tripartite motif-containing protein 10 protein (222-481AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UDY6 |
Uniprot Id
Q9UDY6
Target Species
Human
Target Name
TRIM10
Target Full Name
Tripartite motif-containing protein 10
Target Function
E3 ligase that plays an essential role in the differentiation and survival of terminal erythroid cells. May directly bind to PTEN and promote its ubiquitination, resulting in its proteasomal degradation and activation of hypertrophic signaling. In addition, plays a role in immune response regulation by repressing the phosphorylation of STAT1 and STAT2 in the interferon/JAK/STAT signaling pathway independent of its E3 ligase activity. Mechanistically, interacts with the intracellular domain of IFNAR1 and thereby inhibits the association between TYK2 and IFNAR1.
Target Subcellular Location
Cytoplasm.
Target Protein Families
TRIM/RBCC family
Target Synonyms
TRIM10; RFB30; RNF9; Tripartite motif-containing protein 10; B30-RING finger protein; RING finger protein 9
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