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The antibody against MFNG was raised in rabbit using the Recombinant Human Beta-1,3-N-acetylglucosaminyltransferase manic fringe protein (28-321AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA.
The antibody against MFNG was raised in rabbit using the Recombinant Human Beta-1,3-N-acetylglucosaminyltransferase manic fringe protein (28-321AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA.
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| Cat.No | ADC-01644A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MFNG |
| Target Synonyms | 3-N-acetylglucosaminyltransferase manic fringe; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, MFNG; Beta-1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | Antigen affinity purified |
| Conjugate | Biotin conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Beta-1,3-N-acetylglucosaminyltransferase manic fringe protein (28-321AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O00587 |
Uniprot Id
O00587
Target Species
Human
Target Name
MFNG
Target Full Name
Beta-1,3-N-acetylglucosaminyltransferase manic fringe
Target Function
Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1.
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyltransferase 31 family
Target Synonyms
MFNG; Beta-1,3-N-acetylglucosaminyltransferase manic fringe; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
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