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Rabbit anti-Escherichia coli (strain K12) phoP Polyclonal Antibody

The antibody against phoP was raised in rabbit using the Recombinant Escherichia coli Transcriptional regulatory protein phoP (phoP) (1-223AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Protein A/G purified. This antibody has been validated on ELISA, WB.

ADC-01742A

The antibody against phoP was raised in rabbit using the Recombinant Escherichia coli Transcriptional regulatory protein phoP (phoP) (1-223AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Protein A/G purified. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-01742A ClonalityPolyclonal
Host SpeciesRabbitTarget NamephoP
Target SynonymsphoP antibody; b1130 antibody; JW1116 antibody; Transcriptional regulatory protein PhoP antibodyFormLiquid
Species ReactivityEscherichia coliIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification MethodProtein A/G purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Escherichia coli Transcriptional regulatory protein phoP (phoP) (1-223AA)Target SpeciesEscherichia coli (strain K12)
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP23836
Background Information
  • Uniprot Id

    P23836

  • Target Species

    E.coli

  • Target Name

    PHOP

  • Target Function

    Member of the two-component regulatory system PhoP/PhoQ involved in adaptation to low Mg(2+) environments and the control of acid resistance genes. In low periplasmic Mg(2+), PhoQ phosphorylates PhoP, resulting in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG). In high periplasmic Mg(2+), PhoQ dephosphorylates phospho-PhoP, resulting in the repression of PAG and may lead to expression of some PRG. Mediates magnesium influx to the cytosol by activation of MgtA. Promotes expression of the two-component regulatory system rstA/rstB and transcription of the hemL, mgrB, nagA, slyB, vboR and yrbL genes.

  • Target Subcellular Location

    Cytoplasm.

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