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The antibody against MRAP2 was raised in rabbit using the Recombinant Human Melanocortin-2 receptor accessory protein 2 protein (66-205AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against MRAP2 was raised in rabbit using the Recombinant Human Melanocortin-2 receptor accessory protein 2 protein (66-205AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
Immunofluorescent analysis of U251 cells using MRAP2 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-18610A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MRAP2 |
| Target Synonyms | MRAP2; C6orf117; Melanocortin-2 receptor accessory protein 2; MC2R accessory protein 2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Melanocortin-2 receptor accessory protein 2 protein (66-205AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96G30 |
Uniprot Id
Q96G30
Target Species
Human
Target Name
MRAP2
Target Full Name
Melanocortin-2 receptor accessory protein 2
Target Function
Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP. May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R); however, additional evidence is required in vivo.
Target Involvement
Obesity (OBESITY)
Target Subcellular Location
Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Target Protein Families
MRAP family
Target Tissue Specificity
Expressed in the adrenal gland and brain. Not expressed in other tissues.
Target Synonyms
MRAP2; C6orf117; Melanocortin-2 receptor accessory protein 2; MC2R accessory protein 2
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