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The antibody against INSL4 was raised in rabbit using the Recombinant Human Early placenta insulin-like peptide protein (30-139AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against INSL4 was raised in rabbit using the Recombinant Human Early placenta insulin-like peptide protein (30-139AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human endometrial cancer using INSL4 Antibody at dilution of 1:100
| Cat.No | ADC-20232A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | INSL4 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Early placenta insulin-like peptide protein (30-139AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14641 |
Uniprot Id
Q14641
Target Species
Human
Target Name
INSL4
Target Full Name
Early placenta insulin-like peptide
Target Function
May play an important role in trophoblast development and in the regulation of bone formation.
Target Subcellular Location
Secreted.
Target Protein Families
Insulin family
Target Tissue Specificity
Expressed in placenta, uterus and in fetal perichondrium. Expression levels were increased in both early placentas and molar pregnancies and were reduced in choriocarcinoma cells.
Target Synonyms
early placenta insulin like peptide (EPIL) ; Early placenta insulin like peptide A chain; Early placenta insulin like peptide; Early placenta insulin like peptide B chain; Early placenta insulin-like peptide A chain; EPIL; INSL4; INSL4_HUMAN; insulin like 4 ; insulin like 4 (placenta); Insulin like peptide 4; Insulin-like peptide 4; OTTHUMP00000021025; Placentin
Target Background
INSL4 encodes the insulin-like 4 protein, a member of the insulin superfamily. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains, or just the A and B chains. Expression of INSL4 products occurs within the early placental cytotrophoblast and syncytiotrophoblast.
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