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The antibody against HA was raised in rabbit using the Recombinant Influenza A virus Hemagglutinin protein (1-328AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against HA was raised in rabbit using the Recombinant Influenza A virus Hemagglutinin protein (1-328AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-20541A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HA |
| Target Synonyms | HA antibody; Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain] antibody; Fragment antibody | Form | Liquid |
| Species Reactivity | Influenza A virus | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Influenza A virus Hemagglutinin protein (1-328AA) | Target Species | Influenza A virus (strain A/England/878/1969 H3N2) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P04664 |
Uniprot Id
P04664
Target Species
Influenza A virus
Target Name
HA
Target Function
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
Target Subcellular Location
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Target Protein Families
Influenza viruses hemagglutinin family
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