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Rabbit anti-Human TYRP1 Polyclonal Antibody

The antibody against TYRP1 was raised in rabbit using the Recombinant Human 5,6-dihydroxyindole-2-carboxylic acid oxidase protein (91-186AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.

ADC-02138A

The antibody against TYRP1 was raised in rabbit using the Recombinant Human 5,6-dihydroxyindole-2-carboxylic acid oxidase protein (91-186AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.

$299.00

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Specifications


Cat.No ADC-02138A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTYRP1
Target Synonyms6-dihydroxyindole-2-carboxylic acid oxidase; DHICA oxidase; Catalase B; Glycoprotein 75; Melanoma antigen gp75; Tyrosinase-related protein 1; TRP; TRP-1; TRP1, TYRP1; CAS2; TYRP; TYRRP; 5FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IF
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human 5,6-dihydroxyindole-2-carboxylic acid oxidase protein (91-186AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP17643
Background Information
  • Uniprot Id

    P17643

  • Target Species

    Human

  • Target Name

    TYRP1

  • Target Full Name

    5,6-dihydroxyindole-2-carboxylic acid oxidase

  • Target Function

    Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid in the presence of bound Cu(2+) ions, but not in the presence of Zn(2+). May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin.

  • Target Involvement

    Albinism, oculocutaneous, 3 (OCA3)

  • Target Subcellular Location

    Melanosome membrane; Single-pass type I membrane protein. Melanosome.

  • Target Protein Families

    Tyrosinase family

  • Target Tissue Specificity

    Pigment cells.

  • Target Synonyms

    TYRP1; CAS2; TYRP; TYRRP; 5,6-dihydroxyindole-2-carboxylic acid oxidase; DHICA oxidase; Catalase B; Glycoprotein 75; Melanoma antigen gp75; Tyrosinase-related protein 1; TRP; TRP-1; TRP1

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