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The antibody against NARS was raised in rabbit using the Recombinant Human Asparagine--tRNA ligase, cytoplasmic protein (1-300AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against NARS was raised in rabbit using the Recombinant Human Asparagine–tRNA ligase, cytoplasmic protein (1-300AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human liver cancer using NARS Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using NARS Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-21809A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NARS |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Asparagine--tRNA ligase, cytoplasmic protein (1-300AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43776 |
Uniprot Id
O43776
Target Species
Human
Target Name
NARS1
Target Full Name
Asparagine--tRNA ligase, cytoplasmic
Target Function
Catalyzes the attachment of asparagine to tRNA(Asn) in a two-step reaction: asparagine is first activated by ATP to form Asn-AMP and then transferred to the acceptor end of tRNA(Asn). In addition to its essential role in protein synthesis, acts as a signaling molecule that induced migration of CCR3-expressing cells. Has an essential role in the development of the cerebral cortex, being required for proper proliferation of radial glial cells.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Class-II aminoacyl-tRNA synthetase family
Target Synonyms
3010001M15Rik; AA960128; AsnRS; ASNS; Asparagine tRNA ligase 1; cytoplasmic; Asparagine tRNA ligase; Asparagine--tRNA ligase; Asparaginyl tRNA synthetase; Asparaginyl-tRNA synthetase; C78150; cytoplasmic; EC 6.1.1.22; LRRGT00113 ; MGC116236; Nars; NARS1; NRS; SYNC_HUMAN
Target Background
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Asparaginyl-tRNA synthetase is localized to the cytoplasm and belongs to the class II family of tRNA synthetases. The N-terminal domain represents the signature sequence for the eukaryotic asparaginyl-tRNA synthetases.
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