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The antibody against COPZ1 was raised in rabbit using the Recombinant Human Coatomer subunit zeta-1 protein (1-177AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against COPZ1 was raised in rabbit using the Recombinant Human Coatomer subunit zeta-1 protein (1-177AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human brain tissue using COPZ1 Antibody at dilution of 1:1002
| Cat.No | ADC-22159A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | COPZ1 |
| Target Synonyms | COPZ1 antibody; COPZ antibody; CGI-120 antibody; HSPC181Coatomer subunit zeta-1 antibody; Zeta-1-coat protein antibody; Zeta-1 COP antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Coatomer subunit zeta-1 protein (1-177AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P61923 |
Uniprot Id
P61923
Target Species
Human
Target Name
COPZ1
Target Full Name
Coatomer subunit zeta-1
Target Function
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
Target Subcellular Location
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families
Adaptor complexes small subunit family
Target Synonyms
COPZ1; COPZ; CGI-120; HSPC181Coatomer subunit zeta-1; Zeta-1-coat protein; Zeta-1 COP
Target Background
This gene encodes a subunit of the cytoplasmic coatamer protein complex, which is involved in autophagy and intracellular protein trafficking. The coatomer protein complex is comprised of seven subunits and functions as the coat protein of coat protein complex (COP)I-vesicles. Alternative splicing results in multiple transcript variants.
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