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The antibody against FMNL1 was raised in rabbit using the Recombinant Human Formin-like protein 1 protein (207-457AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against FMNL1 was raised in rabbit using the Recombinant Human Formin-like protein 1 protein (207-457AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human tonsil tissue using FMNL1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using FMNL1 Antibody at dilution of 1:1002
| Cat.No | ADC-22700A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FMNL1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Formin-like protein 1 protein (207-457AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O95466 |
Uniprot Id
O95466
Target Species
Human
Target Name
FMNL1
Target Full Name
Formin-like protein 1
Target Function
May play a role in the control of cell motility and survival of macrophages. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape.
Target Subcellular Location
Cytoplasm. Cell membrane; Lipid-anchor. Cytoplasmic vesicle, phagosome.; [Isoform 3]: Cytoplasm, cell cortex. Cell projection, bleb. Note=Colocalized with F-actin in bleb protrusions.
Target Protein Families
Formin homology family
Target Tissue Specificity
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Target Synonyms
8030453N10Rik; AI553564; C17orf1; C17orf1B; CLL associated antigen KW 13; CLL-associated antigen KW-13; FHOD4; FMNL; FMNL_HUMAN; Fmnl1; Fnrl; Formin like 1; Formin like; Formin related protein; Formin-like protein 1; Frls; KW 13; KW13; Leukocyte formin; MGC133052; MGC1894; MGC21878
Target Background
This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length sequence has not been determined.
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