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The antibody against TTL was raised in rabbit using the Recombinant Human Tubulin--tyrosine ligase protein (1-377AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against TTL was raised in rabbit using the Recombinant Human Tubulin–tyrosine ligase protein (1-377AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-23094A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TTL |
| Target Synonyms | TTL antibody; Tubulin--tyrosine ligase antibody; TTL antibody; EC 6.3.2.25 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Tubulin--tyrosine ligase protein (1-377AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8NG68 |
Uniprot Id
Q8NG68
Target Species
Human
Target Name
TTL
Target Full Name
Tubulin--tyrosine ligase
Target Function
Catalyzes the post-translational addition of a tyrosine to the C-terminal end of detyrosinated alpha-tubulin.
Target Protein Families
Tubulin--tyrosine ligase family
Target Synonyms
TTL; Tubulin--tyrosine ligase; TTL; EC 6.3.2.25
Target Background
TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).
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