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The antibody against PRICKLE3 was raised in rabbit using the Peptide sequence from Human Prickle-like protein 3 protein (9-24AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against PRICKLE3 was raised in rabbit using the Peptide sequence from Human Prickle-like protein 3 protein (9-24AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
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Western Blot_x000D_ | Positive WB detected in: Hela whole cell lysate, Jurkat whole cell lysate, PC-3 whole cell lysate_x000D_ | All lanes: PRICKLE3 antibody at 1:2000_x000D_ | Secondary_x000D_ | Goat polyclonal to rabbit IgG at 1/50000 dilution_x000D_ | Predicted band size: 69, 60 kDa_x000D_ | Observed band size: 69 kDa
| Cat.No | ADC-02488A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PRICKLE3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Peptide sequence from Human Prickle-like protein 3 protein (9-24AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43900 |
Uniprot Id
O43900
Target Species
Human
Target Name
PRICKLE3
Target Full Name
Prickle planar cell polarity protein 3
Target Function
Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gastrulation and neurulation. PCP is maintained by two molecular modules, the global and the core modules, PRICKLE3 being part of the core module. Distinct complexes of the core module segregate to opposite sides of the cell, where they interact with the opposite complex in the neighboring cell at or near the adherents junctions. Involved in the organization of the basal body. Involved in cilia growth and positioning. Required for proper assembly, stability, and function of mitochondrial membrane ATP synthase (mitochondrial complex V).
Target Subcellular Location
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion.
Target Protein Families
Prickle / espinas / testin family
Target Tissue Specificity
Widely expressed.
Target Synonyms
PRICKLE3; LMO6Prickle planar cell polarity protein 3; LIM domain only protein 6; LMO-6; Prickle-like protein 3; Pk3; Triple LIM domain protein 6
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