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The antibody against SETBP1 was raised in rabbit using the Recombinant Human SET-binding protein (1-242AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against SETBP1 was raised in rabbit using the Recombinant Human SET-binding protein (1-242AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-23639A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SETBP1 |
| Target Synonyms | SEB antibody; SET binding protein 1 antibody; SET-binding protein antibody; SETBP 1 antibody; SETBP_HUMAN antibody; Setbp1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Biotin conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human SET-binding protein (1-242AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y6X0 |
Uniprot Id
Q9Y6X0
Target Species
Human
Target Name
SETBP1
Target Full Name
SET-binding protein
Target Involvement
Schinzel-Giedion midface retraction syndrome (SGMFS); Myelodysplastic syndrome (MDS); Mental retardation, autosomal dominant 29 (MRD29); Leukemia, acute myelogenous (AML); Leukemia, chronic myeloid, atypical (ACML); Leukemia, juvenile myelomonocytic (JMML)
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Expressed in numerous tissues. Expressed at low levels in myeloid and monocytic cells as well as in CD34+ cells; expression levels are higher in myeloid malignancies.
Target Synonyms
SEB; SET binding protein 1; SET-binding protein; SETBP 1; SETBP_HUMAN; Setbp1
Target Background
This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
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