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Rabbit anti-Human SAMSN1 Polyclonal Antibody

The antibody against SAMSN1 was raised in rabbit using the Recombinant Human SAM domain-containing protein SAMSN-1 protein (1-373AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

ADC-23705A

The antibody against SAMSN1 was raised in rabbit using the Recombinant Human SAM domain-containing protein SAMSN-1 protein (1-373AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-23705A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSAMSN1
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human SAM domain-containing protein SAMSN-1 protein (1-373AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9NSI8
Background Information
  • Uniprot Id

    Q9NSI8

  • Target Species

    Human

  • Target Name

    SAMSN1

  • Target Full Name

    SAM domain-containing protein SAMSN-1

  • Target Function

    Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation.

  • Target Subcellular Location

    Nucleus. Cytoplasm. Cell projection, ruffle.

  • Target Tissue Specificity

    Detected in peripheral blood B-cells (at protein level). Detected in spleen, liver and peripheral blood.

  • Target Synonyms

    HACS1; Hematopoietic adapter containing SH3 and sterile α, motif (SAM) domains 1; Hematopoietic adapter containing SH3 and sterile alpha motif (SAM) domains 1; Hematopoietic adaptor containing SH3 and SAM domains 1; Nash1; Nuclear localization signals SAM and SH3 domain containing 1; SAM and SH3 domain containing 2; SAM domain; SAM domain containing protein SAMSN 1; SAM domain SH3 domain and nuclear localisation signals 1; SAM domain SH3 domain and nuclear localization signals 1; SAM domain, SH3 domain and nuclear localization signals protein 1; SAM domain-containing protein SAMSN-1; SAMN1_HUMAN; SAMSN 1; Samsn1; SASH2; SH3 domain and nuclear localisation signals 1; SH3 domain and nuclear localization signals protein 1; SH3 SAM adaptor protein; SH3-SAM adaptor protein; SH3D6B; SLy2; Src homology domain 3 (SH3) containing adapter protein SH3 lymphocyte protein 2

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