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The antibody against GPC4 was raised in rabbit using the Recombinant Human Glypican-4 protein (19-210AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against GPC4 was raised in rabbit using the Recombinant Human Glypican-4 protein (19-210AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human pancreatic tissue using GPC4 Antibody at dilution of 1:1002
| Cat.No | ADC-24798A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GPC4 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Glypican-4 protein (19-210AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O75487 |
Uniprot Id
O75487
Target Species
Human
Target Name
GPC4
Target Full Name
Glypican-4
Target Function
Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system.
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.; [Secreted glypican-4]: Secreted, extracellular space.
Target Protein Families
Glypican family
Target Synonyms
dJ900E8.1 glypican 4; Glypican proteoglycan 4; Gpc4; GPC4_HUMAN; K Glypican; K-glypican; Kglypican; OTTHUMP00000024052; Secreted glypican 4; Secreted glypican-4; UNQ474/PRO937
Target Background
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome.
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