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The antibody against CARD19 was raised in rabbit using the Recombinant Human Bcl10-interacting CARD protein (1-183AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against CARD19 was raised in rabbit using the Recombinant Human Bcl10-interacting CARD protein (1-183AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human small intestine tissue using CARD19 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human gastric cancer using CARD19 Antibody at dilution of 1:1002
| Cat.No | ADC-25174A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CARD19 |
| Target Synonyms | Bcl10 interacting protein with CARD protein antibody; Bcl10-interacting CARD protein antibody; BINCA_HUMAN antibody; BinCARD antibody; C9orf89 antibody; Chromosome 9 open reading frame 89 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Bcl10-interacting CARD protein (1-183AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96LW7 |
Uniprot Id
Q96LW7
Target Species
Human
Target Name
CARD19
Target Full Name
Caspase recruitment domain-containing protein 19
Target Function
Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.
Target Subcellular Location
[Isoform 1]: Nucleus. Note=Coexpression with BCL10 induced translocation from nucleus to cytosol.; [Isoform 2]: Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Target Tissue Specificity
Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain.
Target Synonyms
Bcl10 interacting protein with CARD protein; Bcl10-interacting CARD protein; BINCA_HUMAN; BinCARD; C9orf89; Chromosome 9 open reading frame 89
Target Background
Located in mitochondrion.
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