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The antibody against AP3S2 was raised in rabbit using the Recombinant Human AP-3 complex subunit sigma-2 protein (1-193AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against AP3S2 was raised in rabbit using the Recombinant Human AP-3 complex subunit sigma-2 protein (1-193AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-25260A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AP3S2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human AP-3 complex subunit sigma-2 protein (1-193AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P59780 |
Uniprot Id
P59780
Target Species
Human
Target Name
AP3S2
Target Full Name
AP-3 complex subunit sigma-2
Target Function
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Target Subcellular Location
Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families
Adaptor complexes small subunit family
Target Tissue Specificity
Present in all adult tissues examined.
Target Synonyms
Adapter related protein complex 3 sigma 2 subunit; Adapter-related protein complex 3 sigma-2 subunit; AP 3 complex sigma 3B subunit; AP-3 complex subunit sigma-2; AP-3 complex subunit sigma-3B; Ap3s2; AP3S2_HUMAN; Clathrin adaptor complex AP3 sigma 3b subunit; Clathrin associated/assembly/adaptor protein; small 4 22-kD; Sigma 3B adaptin; Sigma adaptin 3b; Sigma-3B-adaptin; Sigma-adaptin 3b; Sigma3B-adaptin
Target Background
Predicted to be involved in anterograde synaptic vesicle transport and vesicle-mediated transport. Located in intracellular membrane-bounded organelle. Part of AP-3 adaptor complex.
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