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The antibody against CST7 was raised in rabbit using the Recombinant Human Cystatin-F protein (20-145AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against CST7 was raised in rabbit using the Recombinant Human Cystatin-F protein (20-145AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human colon cancer using CST7 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver cancer using CST7 Antibody at dilution of 1:1002
| Cat.No | ADC-25339A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CST7 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Cystatin-F protein (20-145AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O76096 |
Uniprot Id
O76096
Target Species
Human
Target Name
CST7
Target Full Name
Cystatin-F
Target Function
Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system.
Target Subcellular Location
Secreted. Cytoplasm.
Target Protein Families
Cystatin family
Target Tissue Specificity
Primarily expressed in peripheral blood cells and spleen.
Target Synonyms
CMAP; CST 7; Cst7; Cystatin 7; cystatin F (leukocystatin); Cystatin like metastasis associated protein; Cystatin-7; Cystatin-F; Cystatin-like metastasis-associated protein; Cystatin7; CystatinF; CYTF_HUMAN; dJ568C11.1; Leukocystatin
Target Background
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. This gene encodes a glycosylated cysteine protease inhibitor with a putative role in immune regulation through inhibition of a unique target in the hematopoietic system. Expression of the protein has been observed in various human cancer cell lines established from malignant tumors.
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