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The antibody against COL8A2 was raised in rabbit using the Synthetic peptide of Human COL8A2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against COL8A2 was raised in rabbit using the Synthetic peptide of Human COL8A2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-25406A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | COL8A2 |
| Target Synonyms | COL8A2Collagen alpha-2(VIII) chain antibody; Endothelial collagen antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human COL8A2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P25067 |
Uniprot Id
P25067
Target Species
Human
Target Name
COL8A2
Target Full Name
Collagen alpha-2(VIII) chain
Target Function
Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.
Target Involvement
Corneal dystrophy, Fuchs endothelial, 1 (FECD1); Corneal dystrophy, posterior polymorphous, 2 (PPCD2)
Target Subcellular Location
Secreted, extracellular space, extracellular matrix, basement membrane.
Target Tissue Specificity
Expressed primarily in the subendothelium of large blood vessels. Also expressed in arterioles and venules in muscle, heart, kidney, spleen, umbilical cord, liver and lung and is also found in connective tissue layers around hair follicles, around nerve b
Target Synonyms
COL8A2Collagen alpha-2(VIII) chain; Endothelial collagen
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