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The antibody against TBXA2R was raised in rabbit using the Synthetic peptide of Human TBXA2R as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against TBXA2R was raised in rabbit using the Synthetic peptide of Human TBXA2R as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-25585A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TBXA2R |
| Target Synonyms | TBXA2R; Thromboxane A2 receptor; TXA2-R; Prostanoid TP receptor | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human TBXA2R | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P21731 |
Uniprot Id
P21731
Target Species
Human
Target Name
TBXA2R
Target Full Name
Thromboxane A2 receptor
Target Function
Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C.; Activates adenylyl cyclase.; Inhibits adenylyl cyclase.
Target Involvement
Bleeding disorder, platelet-type 13 (BDPLT13)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family
Target Synonyms
TBXA2R; Thromboxane A2 receptor; TXA2-R; Prostanoid TP receptor
Target Background
This gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene.
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